何大一谈艾滋病研究的新突破

Matt Lauer: On close up this morning, new hope in the fight against AIDS as we reported, the new study has some scientists excited and others skeptical¹. Doctor David Ho was Time magazine's man of the year in 1996 for his work on the treatment that has slowed the disease in millions of patients. He's a scientific director for AIDS Treatment at Rockefeller University. Dr. Ho, good morning, nice to see you.

Doctor David Ho: Good morning, man.

Matt Lauer: You were not involved in this study, the lead researcher which had it at the University of North Carolina. 4 patients over 3 months were studied in layman's terms if you can. What did this study accomplish that other studies haven't accomplished²?

Doctor David Ho: Well, first, that's began about ten years ago when combination or cocktail³ therapy came along which allow us to control HIV quite well. The actively⁴, the part of HIV that's active in the body could be controlled a thousand times. But there was always a little bit left hiding out in certain cells. And this group of researchers address that hidden pool, so called the reservior, and in this study they were able to lower that modestly in four individuals, so we have to be, it's a very interesting observation, but we have to be cautious in token(not sure) in those results.

Matt Lauer: You said uh lower that modestly, I've read in some places, I'd say it could be reduced by as much as 75 percent. And is that an overstatement?

Doctor David Ho: Ah, any word from about 20 to close to 80 percent, so, but the measurement of this test is not so precise. So we have to consider that modestly.

Matt Lauer: The way has been described to me again in layman's terms is that the, the sleeping cells are activated⁵ by this drug and then knocked down, is that true?

Doctor David Ho: That's the theory, now it remains⁶ to be seen whether the decrease is in fact due to the active drug valproic acid.

Matt Lauer: So, it, it, again, researchers and scientists in this field are loath⁷ to word, to use the word cure,(Sure)but does this present or represent a step in the direction of a possible cure?

Doctor David Ho: Absolutely, I think, now, this study will trigger further investigation⁸ into whether valproic acid indeed would turn on the cells so that the drugs could get at the virus.

Matt Lauer: If, if you can eliminate or lower the amount of cells by between 20 and 80 percent as you say, does that remaining 20 percent that remains in the body still represent the risk of the AIDS does not go away?

Doctor David Ho: It still does, but this is step forward in the sense that we now have a strategy to lower this pool if indeed the study is proven correct later on.

Matt Lauer: Can you just explain a little bit ,doctor, as why, why scientists are so cautious and so careful to raise any hopes when it comes to research like this?

Doctor David Ho: Well, HIV-AIDS has been a devastating⁹ disease and the virus insinuates¹⁰ itself into the chromosome¹¹ of the cells in the body of the infected person, so in theory it's extremely difficult to get rid of, and so scientists do not want to raise false hope, and the disease has been devastating, so, too, so many raising false hope will only add insult to entry.

Matt Lauer: As I've mentioned four patients study there. How large the study do you need before we know more about this particular technique?

Doctor David Ho: I think this study will trigger many studies and some of which will reach 50 or 100 patients to see if this observation could be confirmed.

Matt Lauer: Keep our fingers crossed Dr. David Ho. Thanks for joining us this morning.

1 skeptical   

adj.怀疑的，多疑的

参考例句：

• Others here are more skeptical about the chances for justice being done.这里的其他人更为怀疑正义能否得到伸张。
• Her look was skeptical and resigned.她的表情是将信将疑而又无可奈何。

2 accomplished   

adj.有才艺的；有造诣的；达到了的

参考例句：

• Thanks to your help,we accomplished the task ahead of schedule.亏得你们帮忙,我们才提前完成了任务。
• Removal of excess heat is accomplished by means of a radiator.通过散热器完成多余热量的排出。

3 cocktail   

n.鸡尾酒；餐前开胃小吃；混合物

参考例句：

• We invited some foreign friends for a cocktail party.我们邀请了一些外国朋友参加鸡尾酒会。
• At a cocktail party in Hollywood,I was introduced to Charlie Chaplin.在好莱坞的一次鸡尾酒会上，人家把我介绍给查理·卓别林。

4 actively   

adv.积极地，勤奋地

参考例句：

• During this period all the students were actively participating.在这节课中所有的学生都积极参加。
• We are actively intervening to settle a quarrel.我们正在积极调解争执。

5 activated   

adj. 激活的 动词activate的过去式和过去分词

参考例句：

• The canister is filled with activated charcoal.蒸气回收罐中充满了活性炭。

6 remains   

n.剩余物，残留物；遗体，遗迹

参考例句：

• He ate the remains of food hungrily.他狼吞虎咽地吃剩余的食物。
• The remains of the meal were fed to the dog.残羹剩饭喂狗了。

7 loath   

adj.不愿意的；勉强的

参考例句：

• The little girl was loath to leave her mother.那小女孩不愿离开她的母亲。
• They react on this one problem very slow and very loath.他们在这一问题上反应很慢，很不情愿。

8 investigation   

n.调查，调查研究

参考例句：

• In an investigation,a new fact became known, which told against him.在调查中新发现了一件对他不利的事实。
• He drew the conclusion by building on his own investigation.他根据自己的调查研究作出结论。

9 devastating   

adj.毁灭性的，令人震惊的，强有力的

参考例句：

• It is the most devastating storm in 20 years.这是20年来破坏性最大的风暴。
• Affairs do have a devastating effect on marriages.婚外情确实会对婚姻造成毁灭性的影响。

10 insinuates   

n.暗示( insinuate的名词复数 )；巧妙或迂回地潜入；（使）缓慢进入；慢慢伸入v.暗示( insinuate的第三人称单数 )；巧妙或迂回地潜入；（使）缓慢进入；慢慢伸入

参考例句：

• Slang insinuates itself into the language. 俚语慢慢地渗入语言中。 来自辞典例句
• But the division of labor slowly insinuates itself into this process of production. 但是，分工慢慢地侵入了这种生产过程。 来自英汉非文学 - 家庭、私有制和国家的起源

11 chromosome   

n.染色体

参考例句：

• Chromosome material with exhibits of such behaviour is called heterochromatin.表现这种现象的染色体物质叫做异染色质。
• A segment of the chromosome may become lost,resulting in a deletion.染色体的一个片段可能会丢失，结果产生染色体的缺失。