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This is Scientific American's 60-Second Science. I'm Steve Mirsky. Got a minute?
One of the dreams of biomedical scientists is to be able to transform adult cells into other kinds of cells. And thus avoid some of the ethical1 concerns of working with embryonic2 stem cells. Now a research team from McMaster University in Ontario has announced that they've been able to transform human skin cells into blood cells. The work was published online on November 7th by the journal Nature.
Other research in this area has required that cells of one type first be returned to a more generally undifferentiated stem cell state, which can introduce fresh problems. Once there, the cell is then turned into the type of tissue the researchers seek. But in this case, the scientists avoided the middleman cell. The skin was changed directly into what appears to be functional4 adult human blood cells. The technique involves gene3 insertion by a virus vector and exposure to numerous regulatory proteins.
The cells have not been tested in humans to see if they're truly indistinguishable from the home-grown kind. But the research is another step in the effort to create needed cell types from easily available ones.
Thanks for the minute. For Scientific American's 60-Second Science, I'm Steve Mirsky.
1 ethical | |
adj.伦理的,道德的,合乎道德的 | |
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2 embryonic | |
adj.胚胎的 | |
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3 gene | |
n.遗传因子,基因 | |
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4 functional | |
adj.为实用而设计的,具备功能的,起作用的 | |
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