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(单词翻译:双击或拖选)
Patients undergoing coronary bypass surgery need implants1 of new, healthy blood vessels3. So do those who receive repeated hemodialysis due to kidney failure. The best option is to use the patient's own veins4 or arteries5, but thousands of patients don't have resources available in their own bodies.
Now, scientists have demonstrated ready-to-use, bioengineered blood vessels made from human cells. The work appears in the journal Science Translational Medicine.
Lead author Shannon Dahl explained on the journal's podcast:"We start with human cells from a donor6. And we seed these cells onto a degradable polymeric scaffold…the cells proliferate7 and secrete8 extracellular matrix proteins, which are the proteins in your tissues that give your tissues strength. And during the time of culture, the polymer degrades away. The polymer that we use is actually the same type of polymer that's used in degradable sutures."
What's left is a functional9 blood vessel2. The implants should not trigger an immune response, getting rid of one potential problem for recipients10. And the vessels can be stored for up to a year, so clinics could keep a supply of spare arteries and veins.
1 implants | |
n.(植入身体中的)移植物( implant的名词复数 ) | |
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2 vessel | |
n.船舶;容器,器皿;管,导管,血管 | |
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3 vessels | |
n.血管( vessel的名词复数 );船;容器;(具有特殊品质或接受特殊品质的)人 | |
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4 veins | |
n.纹理;矿脉( vein的名词复数 );静脉;叶脉;纹理 | |
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5 arteries | |
n.动脉( artery的名词复数 );干线,要道 | |
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6 donor | |
n.捐献者;赠送人;(组织、器官等的)供体 | |
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7 proliferate | |
vi.激增,(迅速)繁殖,增生 | |
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8 secrete | |
vt.分泌;隐匿,使隐秘 | |
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9 functional | |
adj.为实用而设计的,具备功能的,起作用的 | |
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10 recipients | |
adj.接受的;受领的;容纳的;愿意接受的n.收件人;接受者;受领者;接受器 | |
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