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Just below the Arctic Circle in northern Sweden sits a town called ?verkalix. It’s home to only about a thousand people. But those inhabitants were the subject of a seminal1 study in human genetics. The research suggests it that what our parents, or even our grandparents ate, whether they grew up during feast or famine, could actually affect our risk of heart disease and diabetes3.
It shows that either calorie restriction4 or excess of the food, can send, depending on the window of your own development, a similar message to the next generation. R. B. a molecular5 biologist of University of Copenhagen.
That trans-generational massage6 is send of course through sperm7 eggs, so B. and his colleagues compare the sperms8 of thirteen lean versus9 ten obese10 men.? And they found that the heavyweights had epigenetic changes to their sperms, meaning additional chemical groups on their DNA11, which affects how their genes12 are expressed. And many of the changes were to sequences known to affect brain development, including genes regulate appetite. But the changes were not permanent. Because when the researchers study the sperms of men under weight loss surgery, he found that many of those genetic2 alterations13 reversed post-surgery, especially the one in areas related to appetite controlThe study is in the journal Cell Metabolism14. The big question now is how much those epigenetic changes actually influence the next generation. B. now compare father’s sperms to the cord bloods of their babies to find out. But the finding suggest a mechanism15 by which our actions, our eating habits, our fitness can affect our children, which might make you wonder what should you be eating. And how long should you be doing push-ups before you conceive your child.
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1 seminal | |
adj.影响深远的;种子的 | |
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2 genetic | |
adj.遗传的,遗传学的 | |
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3 diabetes | |
n.糖尿病 | |
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4 restriction | |
n.限制,约束 | |
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5 molecular | |
adj.分子的;克分子的 | |
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6 massage | |
n.按摩,揉;vt.按摩,揉,美化,奉承,篡改数据 | |
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7 sperm | |
n.精子,精液 | |
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8 sperms | |
精子( sperm的名词复数 ) | |
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9 versus | |
prep.以…为对手,对;与…相比之下 | |
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10 obese | |
adj.过度肥胖的,肥大的 | |
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11 DNA | |
(缩)deoxyribonucleic acid 脱氧核糖核酸 | |
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12 genes | |
n.基因( gene的名词复数 ) | |
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13 alterations | |
n.改动( alteration的名词复数 );更改;变化;改变 | |
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14 metabolism | |
n.新陈代谢 | |
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15 mechanism | |
n.机械装置;机构,结构 | |
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16 optimal | |
adj.最适宜的;最理想的;最令人满意的 | |
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