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(单词翻译:双击或拖选)
探索世界奥秘之The Ghost In Your Genes2(基因外遗传现象) Unit06
If inheritance was not just about DNA3, if these gene1 switches were so important, just what could turn them on or off? Stephanie and Emend Mullins have two children, Karen and Charlotte.
When we were trying to conceive, and you see all your friends around you, getting pregnant, having children. As each month went on, you become more and more desperate.
Doctors recommended IVF treatment. In the UK alone, around 8,000 babies are conceived every year using assisted reproduction techniques, like IVF. After the third attempt, Stephanie became pregnant with Karen.
At the time, they, they didn't really highlight any risks to us. And then we went for a routine scan. And I did feel that the scan was taking an awful long time. Basically what they'd found was something called exomphalos, em, on Karen's abdomen4 which basically means that part of the bowel5 is still on the outside of the abdomen.
Doctor suspected that Karen might be suffering from Beckwith-Wiedemann syndrome6, a rare condition where babies are born very large, often have oversized tongues and have a high risk of developing childhood cancers.
They couldn't say 100 percent that the baby did have Beckwith-Wiedemann syndrome. But, it was showing signs. They could see his tongue protruding7 on the scan. And he said the beast had very big thighs9. But until Karen was actually born, we didn't know how severely10 affected11 it was going to be.
When Karen was born, it was clear he did indeed have Beckwith-Wiedemann syndrome.
Within a few hours of the birth, Karen had to have surgery to have the bowel that was on the outside of the abdomen basically put back inside repaired. Karen also had surgery to reduce the size of his tongue. And every few months, he has scans to check for tumors.
Good boy, Karen, you're a very, very good boy indeed.
Cases of Beckwith-Wiedemann syndrome caught the attention of Wolf Reik. Wolf Reik worked in developmental genetics. He was fascinated by this emerging epigenetic ghost world. He wanted to know what could throw the switches on or off. To his surprise, he found that simply placing a mouse embryo12 in a culture dish could trigger genes to switch off.
New Words & Phrases:
IVF: IVF is a method of helping13 a woman to have a baby in which an egg is removed from one of her ovaries, fertilized14 outside her body, and then replaced in her womb. IVF is an abbreviation for `in vitro fertilization'. 试管受精
protrude15 : If something protrudes16 from somewhere, it sticks out. 伸出,突出
thigh8: Your thighs are the top parts of your legs, between your knees and your hips17. 大腿
embryo: An embryo is an unborn animal or human being in the very early stages of development. 胚芽;胚胎
1 gene | |
n.遗传因子,基因 | |
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2 genes | |
n.基因( gene的名词复数 ) | |
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3 DNA | |
(缩)deoxyribonucleic acid 脱氧核糖核酸 | |
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4 abdomen | |
n.腹,下腹(胸部到腿部的部分) | |
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5 bowel | |
n.肠(尤指人肠);内部,深处 | |
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6 syndrome | |
n.综合病症;并存特性 | |
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7 protruding | |
v.(使某物)伸出,(使某物)突出( protrude的现在分词 );凸 | |
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8 thigh | |
n.大腿;股骨 | |
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9 thighs | |
n.股,大腿( thigh的名词复数 );食用的鸡(等的)腿 | |
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10 severely | |
adv.严格地;严厉地;非常恶劣地 | |
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11 affected | |
adj.不自然的,假装的 | |
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12 embryo | |
n.胚胎,萌芽的事物 | |
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13 helping | |
n.食物的一份&adj.帮助人的,辅助的 | |
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14 Fertilized | |
v.施肥( fertilize的过去式和过去分词 ) | |
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15 protrude | |
v.使突出,伸出,突出 | |
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16 protrudes | |
v.(使某物)伸出,(使某物)突出( protrude的第三人称单数 ) | |
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17 hips | |
abbr.high impact polystyrene 高冲击强度聚苯乙烯,耐冲性聚苯乙烯n.臀部( hip的名词复数 );[建筑学]屋脊;臀围(尺寸);臀部…的 | |
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