纪录片《节食还是截寿》 第22期:与衰老有关的疾病（在线收听）

This discovery helped Valter

这一发现使得瓦尔特

piece together role that IGF-1 plays

弄清了类胰岛素一号生长因子

in the complicated business of ageing.

在衰老这一复杂过程中的作用

Our bodies are normally in go-go mode-

我们的身体通常是处于加油模式

cells constantly driven to divide by IGF-1.

类胰岛素一号生长因子不断促使细胞分裂

But when IGF-1 levels drop,

但当类胰岛素一号生长因子水平降低时

our cells shift into a completely different mode.

细胞活动将转换到另一种完全不同的模式

The body slows production of new cells

身体产生新细胞的速率降低

and starts repairing existing ones instead.

并开始修复原有细胞

DNA damage is more likely to get fixed.

DNA损伤很可能会得以修复

And that's why the mice AND the villagers

所以那只小鼠和那些村民

are protected from age-related diseases.

不会得与衰老有关疾病的原因

But what's the link to calorie restriction in humans?

那这和低热量饮食有什么关系呢

Valter has lined up a very simple,

瓦尔特作了一个非常简单

very Californian analogy.

非常加州风格的类比