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(单词翻译:双击或拖选)
By Deborah Block
Washington, D.C.
26 June 2006
watch Bird Flu report
Researchers are working on developing vaccines2 for bird flu before it becomes a worldwide epidemic3. The University of Massachusetts Medical School in the United States has teamed with a British drug company to come up with a potential vaccine1 using bird flu DNA4.
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Bird Flu Virus
Traditional flu vaccines use weakened flu viruses and take months to produce on a large scale.
The bird flu DNA vaccine could be easily duplicated and produced in large quantities. DNA is a molecule5 found in a cell that contains a specific genetic6 blueprint7. The DNA-based vaccine would be inserted using a pressurized gun that penetrates8 the skin without using needles.
So far, it appears the bird flu virus has spread only to people who handle poultry9 or have eaten contaminated meat. It has killed more than 125 people worldwide, as well as large poultry flocks in Asia, Europe and Africa. Experts fear millions of people could die in the future if the virus combines with human flu strains and produces a new strain that is highly contagious10 to people.
Dr. Shan Lu
Dr. Shan Lu is with the University of Massachusetts Medical School. "Clearly the bird flu is spreading to more places. The question is when they will jump to humans. That is the question we don't know, but we have to prepare."
Researchers are trying to figure out how the tiny organism replicates11, so it can be stopped from spreading. Waterfowl and other migratory12 birds can tolerate the organism, secreting13 it as waste into ponds, lakes and rivers. But the virus becomes deadly to humans when it infects birds that live on land, particularly chickens. Right now the only way to control bird flu is to slaughter14 diseased poultry.
Daniel Perez
Daniel Perez is head of a bird flu research program at the University of Maryland. He is unsure whether the vaccine, if proven effective, would stop a worldwide epidemic since bird flu viruses mutate, changing constantly.
"The virus is completely unpredictable. I think one of the biggest questions would be how many doses we have to make, how soon we have to have them, because if it [an epidemic] happens tomorrow, we don't have them," warns Mr. Perez.
The vaccine will be tested on animals soon. Human trials are expected in about six months.
1 vaccine | |
n.牛痘苗,疫苗;adj.牛痘的,疫苗的 | |
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2 vaccines | |
疫苗,痘苗( vaccine的名词复数 ) | |
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3 epidemic | |
n.流行病;盛行;adj.流行性的,流传极广的 | |
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4 DNA | |
(缩)deoxyribonucleic acid 脱氧核糖核酸 | |
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5 molecule | |
n.分子,克分子 | |
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6 genetic | |
adj.遗传的,遗传学的 | |
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7 blueprint | |
n.蓝图,设计图,计划;vt.制成蓝图,计划 | |
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8 penetrates | |
v.穿过( penetrate的第三人称单数 );刺入;了解;渗透 | |
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9 poultry | |
n.家禽,禽肉 | |
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10 contagious | |
adj.传染性的,有感染力的 | |
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11 replicates | |
复制( replicate的第三人称单数 ); 重复; 再造; 再生 | |
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12 migratory | |
n.候鸟,迁移 | |
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13 secreting | |
v.(尤指动物或植物器官)分泌( secrete的现在分词 );隐匿,隐藏 | |
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14 slaughter | |
n.屠杀,屠宰;vt.屠杀,宰杀 | |
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