-
(单词翻译:双击或拖选)
Dogs Against Rabies in East Africa
Rabies is a global health issue, claiming fifty to sixty thousand lives every year. Most of these deaths occur in sub-Saharan Africa and South Asia. The rabies virus is usually transmitted to humans through the bite of an infected dog. Because children are the most susceptible1 to attacks by rabid dogs, they account for the vast majority of deaths.
Veterinarian Guy Palmer is conducting research in Tanzania on a sustainable rabies vaccination2 program.
Palmer explained, “If we can get around 60% we can actually control a disease outbreak. We don’t need to vaccinate3 every dog. We need to vaccinate somewhere around 60%. So, the question becomes, can you actually achieve that level of vaccination in a low resource setting?”
Palmer has a PhD in infectious diseases and is an adviser4 to the Global Development Program at the Bill and Melinda Gates Foundation.
He and his colleagues work with community leaders to arrange dog vaccination clinics. Word spreads quickly and people gather with their animals. But Dr. Palmer was surprised when he saw the dog owners.
“Children own these dogs,” he said. “They bring with them their vaccination cards and it’s amazing the percentage that we have that have the vaccination card from a previous trip. We come every year to each village. In general, these families don’t have a lot of papers and certificates. They tend to put a value on those they have.”
While the vaccination effort has been successful, Palmer says there’s more to do to make it sustainable over the long-term.
“We now have about 15 years of experience with this. And if you continue these vaccination campaigns, you completely suppress rabies. The challenge is how do you get away from this model we have now, which is donor5 driven. It costs us about three dollars to vaccinate a dog in those regions and that’s not something that’s, at the moment, sustainable by either the individuals nor by the government. Using country-wide approaches, it’s possible to actually move rabies out of a region and then vaccinate only around the periphery6 to control the disease. To do that what we’ve really got to do is reduce costs,” he said.
About one dollar of the vaccine7 cost is keeping it cold. Fortunately, silk polymers have the potential to revolutionize the storage of vaccines9. Strands10 of silk proteins are purified from silkworm cocoons11 and are incorporated into the vaccine serum12. The silk polymers don’t affect the vaccine’s effectiveness, but they stabilize13 the serum so that it doesn’t degrade under high temperatures. These polymers can protect vaccines at up to 45 degrees Celsius14 for more than six months. The vaccines remain more than eighty percent potent8 despite storage at these temperatures.
Dr. Palmer says there’s another way to reduce costs, as well.
“Working with the communities to get them to vaccinate is one of the major goals we have because that will reduce one of our other major costs, which is transport. If we can actually get the vaccines there, then they can maintain them locally and do the local vaccinations,” he said.
Dr. Palmer’s rabies vaccination studies may present other healthcare opportunities. The vaccination clinics could also be used to provide care and treatment for children when they bring their dogs to be vaccinated15.
1 susceptible | |
adj.过敏的,敏感的;易动感情的,易受感动的 | |
参考例句: |
|
|
2 vaccination | |
n.接种疫苗,种痘 | |
参考例句: |
|
|
3 vaccinate | |
vt.给…接种疫苗;种牛痘 | |
参考例句: |
|
|
4 adviser | |
n.劝告者,顾问 | |
参考例句: |
|
|
5 donor | |
n.捐献者;赠送人;(组织、器官等的)供体 | |
参考例句: |
|
|
6 periphery | |
n.(圆体的)外面;周围 | |
参考例句: |
|
|
7 vaccine | |
n.牛痘苗,疫苗;adj.牛痘的,疫苗的 | |
参考例句: |
|
|
8 potent | |
adj.强有力的,有权势的;有效力的 | |
参考例句: |
|
|
9 vaccines | |
疫苗,痘苗( vaccine的名词复数 ) | |
参考例句: |
|
|
10 strands | |
n.(线、绳、金属线、毛发等的)股( strand的名词复数 );缕;海洋、湖或河的)岸;(观点、计划、故事等的)部份v.使滞留,使搁浅( strand的第三人称单数 ) | |
参考例句: |
|
|
11 cocoons | |
n.茧,蚕茧( cocoon的名词复数 )v.茧,蚕茧( cocoon的第三人称单数 ) | |
参考例句: |
|
|
12 serum | |
n.浆液,血清,乳浆 | |
参考例句: |
|
|
13 stabilize | |
vt.(使)稳定,使稳固,使稳定平衡;vi.稳定 | |
参考例句: |
|
|
14 Celsius | |
adj.摄氏温度计的,摄氏的 | |
参考例句: |
|
|
15 vaccinated | |
[医]已接种的,种痘的,接种过疫菌的 | |
参考例句: |
|
|