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Study: Preterm Birth Complications Leading Cause of Death for Young Children 早产并发症是导致婴幼儿死亡的第一大死因
Complications from preterm births now outrank all other causes of death for young children. Of the more than 6.3 million deaths of kids under age five in 2013, more than one million resulted from preterm problems.
The new study was released November 17, World Prematurity1 Day, and appears in The Lancet medical journal. It’s a collaborative effort by researchers from the Johns Hopkins Bloomberg School of Public Health, the London School of Hygiene3 and Tropical Medicine and the World Health Organization.
The vast majority the deaths from direct complications of preterm births occurred within the first 28 days of life – with an additional 125,000 deaths occurring between one month and five years.
Dr. Andres de Francisco, interim4 executive director of the Geneva-based Partnership5 for Maternal6 Newborn and Child Health, said, “Over the last few years the proportion of deaths due to preterm births has been increasing. The reason for this is that we do not really have major interventions7 in place to avoid premature8 births -- and second, to manage them in most communities where they occur.”
He said preterm birth complications are a worldwide problem.
“We have countries in Africa, for example – Nigeria – or in Asia -- India and Pakistan -- that have extremely high numbers of kids that are dying related to preterm births. But this is not only a problem in developing countries," de Francisco said. "This is also a problem that affects developed countries, as well.”
India actually tops the list, followed by Nigeria, Pakistan, the DRC, China, Bangladesh, Indonesia, Ethiopia, Angola and Kenya. Researchers warn the Ebola outbreak in West Africa raises the risk of preterm complications in the affected9 countries.
The rise in deaths from preterm birth complications actually coincides with a dramatic decline in the worldwide mortality rate of children under five.
“Mortality has been reducing by about 3.9 percent per year, which is a very impressive reduction of mortality -- and is due to a lot of interventions that we have in stock, including decreasing the mortality due to infectious diseases, such as pneumonia10 and diarrhea, malaria11, among others,” de Francisco said.
Some of the interventions credited for the mortality rate decline include vaccines12, bed nets, antibiotics13, anti-malarial and HIV treatments.
But de Francisco said the mortality rate for premature babies has decreased by a much smaller rate of 2 percent a year. A big part of the reason, he says, is a lack of adequate interventions. And, right now, it’s not clear what the best interventions are, aside from addressing obesity14 and high blood pressure or hypertension.
The study said for the most part it’s not fully15 known what triggers pre-term labor2 – and about half of pre-term births occur spontaneously.
“This cause of mortality needs to be studied much more specifically and in a much more focused way. Because if we don’t have the causes – if we don’t have the factors – pregnancy16 is going to end in a premature birth. And this needs to be the focus of intensive research,” de Francisco said.
Some $250 million worth of intensive research is getting underway through four major initiatives: the Global Coalition17 to Advance Preterm Birth Research; the March of Dimes18; the University of California at San Francisco’s Preterm Birth Initiative; and the Global Alliance to Prevent Prematurity and Stillbirth.
“If we are able to support these research programs, within the next five years or so, we will be able to have interventions that are going to contribute to the reduction of mortality in these very small babies,” he said.
Researchers also will study poverty, nutrition, pollution and stress. And they’ll try to solve a mystery: why do Somali women living in the United States have “very low rates of premature births, while most black women in the U.S. have very high rates.”
1 prematurity | |
n.早熟,过早,早开花 | |
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2 labor | |
n.劳动,努力,工作,劳工;分娩;vi.劳动,努力,苦干;vt.详细分析;麻烦 | |
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3 hygiene | |
n.健康法,卫生学 (a.hygienic) | |
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4 interim | |
adj.暂时的,临时的;n.间歇,过渡期间 | |
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5 partnership | |
n.合作关系,伙伴关系 | |
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6 maternal | |
adj.母亲的,母亲般的,母系的,母方的 | |
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7 interventions | |
n.介入,干涉,干预( intervention的名词复数 ) | |
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8 premature | |
adj.比预期时间早的;不成熟的,仓促的 | |
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9 affected | |
adj.不自然的,假装的 | |
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10 pneumonia | |
n.肺炎 | |
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11 malaria | |
n.疟疾 | |
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12 vaccines | |
疫苗,痘苗( vaccine的名词复数 ) | |
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13 antibiotics | |
n.(用作复数)抗生素;(用作单数)抗生物质的研究;抗生素,抗菌素( antibiotic的名词复数 ) | |
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14 obesity | |
n.肥胖,肥大 | |
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15 fully | |
adv.完全地,全部地,彻底地;充分地 | |
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16 pregnancy | |
n.怀孕,怀孕期 | |
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17 coalition | |
n.结合体,同盟,结合,联合 | |
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18 dimes | |
n.(美国、加拿大的)10分铸币( dime的名词复数 ) | |
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