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WHO Approves Infant Meningitis Vaccine1 世界卫生组织已批准婴儿脑膜炎疫苗
The World Health Organization has approved the use of a meningitis vaccine for infants in sub-Saharan Africa. The vaccine has been given to older children and young adults for the past four years.
The WHO said the MenAfriVac vaccine meets international standards for quality, safety and efficacy and now can be used for children under one year of age.
It immunizes against meningitis A – a bacterial2 disease that causes inflammation of membranes3 surrounding the brain and spinal4 cord. The U.S. Centers for Disease Control and Prevention says it can kill within hours – and poses a threat to 450-million people in the so-called “meningitis belt.” The belt consists of 26 countries stretching from Senegal in West Africa to Ethiopia in the East.
The CDC said one in 10 people will die from meningitis A even when antibiotics5 are given. And one out of four survivors6 may be left with paralysis7, blindness, hearing loss and seizures8.
Dr. Marie-Pierre Préziosi is director of the Meningitis Vaccine Project – a partnership9 between the World Health Organization and PATH, a non-profit health organization. She said that meningitis has been a threat in parts of Africa for about 100 years.
“Based on the call from countries, the global health community came about with this project. And the project and its partners developed a vaccine – licensed10 it – and introduced it for mass vaccination11 campaigns. So this has been a tremendous success. And populations from one to 29 years of age are now protected,” she said
But she said it’s now important to extend that protection to infants.
“If we just stop there and don’t provide countries with tour de force sustainability in 10 [or] 15 years from now this massive epidemic12 will return because there will be [an] accumulation of susceptible13 persons in the population. Therefore, there was the need to adapt a vaccine for use in routine immunization in the youngest, in the infants. And this is the purpose of the current licensure and recommendation.”
Dr. Préziosi said the MenAfriVac vaccine offers protection against meningitis A for up to five years. But follow-up studies will be done to monitor the length of its effectiveness. Asked if there are any safety concerns, she said, “No, no safety concern. These conjugate14 vaccines15 are extremely safe.”
Meningitis A is spread from person to person.
“The only reservoir is human beings," she said.
The bacteria can be spread in respiratory droplets16 when a person sneezes, coughs, talks or even laughs.
The head of the Meningitis Vaccine Project said since the vaccine was introduced four years ago about 217-million people have been immunized. Another 100-million are expected to be vaccinated17 in the next few years. The meningitis vaccine is expected to become part of routine immunizations and given to 30-million infants a year in the meningitis belt.
The MenAfriVac vaccine costs less than a dollar per dose. The GAVI Alliance is picking half the cost in the first year of mass immunizations with individual countries paying the rest. GAVI is a public/private partnership that works to increase access to vaccines in poor countries. After the initial mass immunization, the cost gradually shifts to the countries.
1 vaccine | |
n.牛痘苗,疫苗;adj.牛痘的,疫苗的 | |
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2 bacterial | |
a.细菌的 | |
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3 membranes | |
n.(动物或植物体内的)薄膜( membrane的名词复数 );隔膜;(可起防水、防风等作用的)膜状物 | |
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4 spinal | |
adj.针的,尖刺的,尖刺状突起的;adj.脊骨的,脊髓的 | |
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5 antibiotics | |
n.(用作复数)抗生素;(用作单数)抗生物质的研究;抗生素,抗菌素( antibiotic的名词复数 ) | |
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6 survivors | |
幸存者,残存者,生还者( survivor的名词复数 ) | |
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7 paralysis | |
n.麻痹(症);瘫痪(症) | |
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8 seizures | |
n.起获( seizure的名词复数 );没收;充公;起获的赃物 | |
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9 partnership | |
n.合作关系,伙伴关系 | |
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10 licensed | |
adj.得到许可的v.许可,颁发执照(license的过去式和过去分词) | |
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11 vaccination | |
n.接种疫苗,种痘 | |
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12 epidemic | |
n.流行病;盛行;adj.流行性的,流传极广的 | |
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13 susceptible | |
adj.过敏的,敏感的;易动感情的,易受感动的 | |
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14 conjugate | |
vt.使成对,使结合;adj.共轭的,成对的 | |
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15 vaccines | |
疫苗,痘苗( vaccine的名词复数 ) | |
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16 droplets | |
n.小滴( droplet的名词复数 ) | |
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17 vaccinated | |
[医]已接种的,种痘的,接种过疫菌的 | |
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