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Not a new idea
Using EP-MRSI to treat mental illness is a completely different approach only because of the way the magnetism is applied2 to the brain. The notion that the brain might respond to magnets and electricity actually goes way back. Franz Anton Mesmer, an 18th-century Swiss physician, developed a theory that the human nervous system was magnetized, just like the Earth. He developed a variety of treatments using magnets, and even claimed to have restored sight to a blind musician.
The EP-MRSI study is an example of burgeoning3 new research on an old idea—that the brain is an electromagnetic organ and that brain disorders4 might result from disarray5 in magnetic function. The idea has huge appeal to psychiatrists6 and patients alike, since for many people the side effects of psychiatric drugs are almost as difficult to manage as the disease itself. Also, 30 percent of the nearly 18.8 million Americans who suffer from depression do not respond to any of the antidepressants available now.
A new hope for mental illness
What is it about the brain that makes it especially receptive to electromagnetic stimulation7? A partial answer can be found in the neuron, the electrically and chemically excitable nerve cell that receives, processes and transmits information in the brain. When neurons are activated8 by magnets or electricity, the nature of their signals changes—affecting everything from mood to cognition and memory.
“This is a completely different approach in trying to help the brain than anything that was done before”
Most fascinating, perhaps, and most complicating9, is the fact that the brain is dynamic, always in physiological10 flux11. What these recent experiments most vividly12 illustrate13 is the complexity14 of the brain’s pathways, the intricacy of its connections, and the concrete hope that may be offered by the power of a magnet to those suffering from the anguish15 of mental illness.
Vocabulary Focus
disarray (n) [7disE5rei] the state of being confused and lacking organization
side effect (n phr) an unpleasant effect of a drug or therapy that happens in addition to the main effect
flux (n) [flQks] continuous change
intricacy (n) [5intrikEsi] the condition of having a lot of small parts or details that are arranged in a complicated way and are therefore sometimes difficult to understand, solve or produce
Specialized16 Terms
antidepressant (n) 抗抑郁剂 a drug used to reduce feelings of sadness and anxiety
cognition (n) 认知 the act of thinking or using a conscious mental process
电磁与大脑
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并非创举
使用核磁共振成像治疗精神疾病并非创新,但在此过程中电磁运用于脑部却是崭新的疗法。脑部可能对磁场或电流产生反应的概念其实早已存在。18世纪的瑞士医师法兰兹安东麦斯默提出一项理论,认为人体神经系统与地球一样,是有磁性的。麦斯默医师因此研发出各种使用磁力的治疗方式,并宣称曾使一位失明的音乐家重见光明。
人脑是一电磁性器官,而磁性一旦失序,便可能导致脑部疾病——而核磁共振成像研究只是针对此一古老概念的新兴研究之一罢了。对多数人而言,由于精神疾病药物的不良反应,与疾病本身同样难以控制,所以此观念对精神病医师与病患而言,深具吸引力。而且,在约1880万的抑郁症患者中,有30%对目前的抗抑郁药品并无任何反应。
精神疾病的新希望
人脑为何对于电磁刺激有如此之反应?人体的神经元可能提供部分答案。神经元是可经由电流或化学作用刺激的神经细胞,负责接收、处理及传送讯息至脑部。当神经元经由磁性或电流激活时,其所传递的讯号因此改变,进而影响情绪、认知及记忆。
最引人入胜,或许也是最复杂之处,便是人脑其实是动态的,且不断处于生理变迁状态。这些近期实验明确显示脑部错综复杂的线路与连接,以及电磁的力量如何可为饱受精神疾病之苦的病患,带来具体希望。
1 magnetism | |
n.磁性,吸引力,磁学 | |
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2 applied | |
adj.应用的;v.应用,适用 | |
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3 burgeoning | |
adj.迅速成长的,迅速发展的v.发芽,抽枝( burgeon的现在分词 );迅速发展;发(芽),抽(枝) | |
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4 disorders | |
n.混乱( disorder的名词复数 );凌乱;骚乱;(身心、机能)失调 | |
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5 disarray | |
n.混乱,紊乱,凌乱 | |
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6 psychiatrists | |
n.精神病专家,精神病医生( psychiatrist的名词复数 ) | |
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7 stimulation | |
n.刺激,激励,鼓舞 | |
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8 activated | |
adj. 激活的 动词activate的过去式和过去分词 | |
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9 complicating | |
使复杂化( complicate的现在分词 ) | |
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10 physiological | |
adj.生理学的,生理学上的 | |
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11 flux | |
n.流动;不断的改变 | |
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12 vividly | |
adv.清楚地,鲜明地,生动地 | |
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13 illustrate | |
v.举例说明,阐明;图解,加插图 | |
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14 complexity | |
n.复杂(性),复杂的事物 | |
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15 anguish | |
n.(尤指心灵上的)极度痛苦,烦恼 | |
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16 specialized | |
adj.专门的,专业化的 | |
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