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This is Scientific American's 60-Second Science. I'm Steve Mirsky. Got a minute?
The 2011 Nobel Prize in Physiology1 or Medicine goes to Bruce Beutler at the Scripps Research Institute in California, Jules Hoffmann at the French National Center for Scientific Research and Ralph Steinman at Rockefeller University in New York City. Beutler and Hoffman helped to elucidate2 innate3 immunity4. That's the non-specific array of initial responses by the body's immune system that can recognize invading microorganisms as being foreign and try to destroy them.
Steinman investigated dendritic cells, and their key role in what's called adaptive immunity—the specialized5 response to specific invaders6 that comes into play when innate immunity isn't enough. Thanks to adaptive immunity infected cells get wiped out, and exposure to a specific pathogen can leave us with long-standing protection against that pathogen.
The detailed7 understanding of the immune system provided by the new Nobel laureates has given other researchers the ability to improve vaccines8 and to attempt to stimulate9 immune reactions to cancer. Their insights also inform efforts to damp down the immune system when it becomes too zealous10, which can lead to excessive inflammation and autoimmunity.
Thanks for the minute. For Scientific American's 60-Second Science, I'm Steve Mirsky.
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1 physiology | |
n.生理学,生理机能 | |
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2 elucidate | |
v.阐明,说明 | |
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3 innate | |
adj.天生的,固有的,天赋的 | |
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4 immunity | |
n.优惠;免除;豁免,豁免权 | |
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5 specialized | |
adj.专门的,专业化的 | |
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6 invaders | |
入侵者,侵略者,侵入物( invader的名词复数 ) | |
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7 detailed | |
adj.详细的,详尽的,极注意细节的,完全的 | |
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8 vaccines | |
疫苗,痘苗( vaccine的名词复数 ) | |
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9 stimulate | |
vt.刺激,使兴奋;激励,使…振奋 | |
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10 zealous | |
adj.狂热的,热心的 | |
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