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This is the VOA Special English Health Report.
Sleeping sickness is a deadly disease that infects about sixty thousand people in Africa each year. Now scientists in Scotland say they may have found a new treatment. Their findings are in the journal Science.
Sleeping sickness is spread by the bite of the tsetse fly. The insect can carry a parasite1 that infects the central nervous system. First the infection causes fever, headache, itchy skin and weakness.
Then, when the parasite enters the brain, it causes more serious problems. People suffer seizures2 and thinking problems, and they sleep for extended periods. If the disease is not treated, it almost always kills the victim.
Paul Wyatt at the Drug Discovery for Tropical Diseases program at the University of Dundee led the study. He says the research identified a weakness in the parasite. The weakness is an enzyme3 called N-myristoyl transferase, or NMT. The parasite needs NMT to survive.
The researchers developed a mixture of chemicals that interfered4 with the performance of the enzyme. They tried it in test tubes containing the parasites5. As a result, the parasites stopped reproducing.
The tsetse spreads sleeping sickness through its bite
The scientists also tested the treatment on laboratory mice with sleeping sickness. They gave them the chemical compound by mouth and say the infection disappeared.
Now, Paul Wyatt says a drug based on the research could be ready for testing in humans within eighteen months. Currently, medicine for sleeping sickness requires a series of injections that are costly6 and painful. Hospital stays are also needed. And the side effects of the treatment can be serious, sometimes even causing death.
Francois Chappuis is a specialist in neglected tropical diseases with the international group Doctors Without Borders. He says a less costly, easy-to-use medicine for sleeping sickness is badly needed.
FRANCOIS CHAPPUIS: "In areas where the sleeping sickness is still very prevalent, such as remote areas of some central African countries -- which are by the way very unstable7 areas -- it will be also crucial to have simpler treatment and obviously oral treatment would be the best.”
And that's the VOA Special English Health Report, written by Caty Weaver8. Transcripts9 and MP3s of our reports are at voaspecialenglish.com. You can also find us on Twitter and YouTube. And you can join the community at the new VOA Learning English fan page on Facebook. We're at VOA Learning English. I’m Steve Ember.
1 parasite | |
n.寄生虫;寄生菌;食客 | |
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2 seizures | |
n.起获( seizure的名词复数 );没收;充公;起获的赃物 | |
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3 enzyme | |
n.酵素,酶 | |
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4 interfered | |
v.干预( interfere的过去式和过去分词 );调停;妨碍;干涉 | |
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5 parasites | |
寄生物( parasite的名词复数 ); 靠他人为生的人; 诸虫 | |
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6 costly | |
adj.昂贵的,价值高的,豪华的 | |
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7 unstable | |
adj.不稳定的,易变的 | |
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8 weaver | |
n.织布工;编织者 | |
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9 transcripts | |
n.抄本( transcript的名词复数 );转写本;文字本;副本 | |
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