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(单词翻译:双击或拖选)
By Jessica Berman
Washington
23 February 2006
George Khoury, left, a pharmacy1 owner shows different treatments for Malaria2 for sale at his pharmacy in the city of Dakar, Senegal (File photo - Nov. 17, 20)
Doctors in Senegal are reporting they have developed an effective way of protecting young children against malaria using antibiotics3. The strategy has to do with how often the drugs are given to the children during the malaria season.
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It is common in Senegal and other countries where malaria is endemic to give young children a small dose of antibiotics every day or week during malaria season to try to keep them from becoming ill.
Most of the one million people who die every year from the mosquito-borne illness are children living in Africa.
But the strategy using drugs as a prevention measure has backfired.
Physician Badara Cisse, who works in rural Senegal, says many children have become resistant4 to the antibiotics, because of overuse and misuse5. He says this happened with a popular drug used to treat malaria.
"That's why we lost chloroquine. And that was very sad for us losing chloroquine, because it was not expensive and it was very effective and not expensive," he noted6.
Cisse and colleagues developed a strategy they hoped would protect children, and prevent drug resistance.
In a study published in the February 25 issue of the medical journal, The Lancet, the authors say they gave 1,000 children under five in rural Senegal a full, two-drug combination of antibiotics once a month during malaria season, when the risk of infection and death is high.
Dr. Badara Cisse, one of the study authors, says this regimen worked.
"We reduced the number of clinical episodes of malaria by 86 percent by using such this approach for preventing malaria," he said.
However, Cisse says it will be some time before this prevention method can be put into practice in Senegal or anywhere else. Cisse says a much larger study must now be conducted to confirm that the regimen is effective.
1 pharmacy | |
n.药房,药剂学,制药业,配药业,一批备用药品 | |
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2 malaria | |
n.疟疾 | |
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3 antibiotics | |
n.(用作复数)抗生素;(用作单数)抗生物质的研究;抗生素,抗菌素( antibiotic的名词复数 ) | |
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4 resistant | |
adj.(to)抵抗的,有抵抗力的 | |
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5 misuse | |
n.误用,滥用;vt.误用,滥用 | |
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6 noted | |
adj.著名的,知名的 | |
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