2006年VOA标准英语-US Government Study Confirms Genetic Basis

By David McAlary
Washington
21 April 2006

New research adds more evidence that chronic¹ fatigue² syndrome³ is a real disease, with a biological basis. U.S. health officials have released several studies showing that people who suffer the malady⁴ have a genetic⁵ makeup⁶ that affects the body's ability to adapt to life's stresses.

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Chronic fatigue syndrome was first identified in the 1980s, but the cause has been elusive⁷. It feels like several days without sleep, a flu-like condition that drains energy and is often accompanied by weakness, headaches, sore joints⁸ and lymph nodes, and impaired⁹ memory.  Bed rest offers no cure.  Women are diagnosed with it two-to-four times as often as men.

Some experts thought the condition might be something else, like mononucleosis, a virus, or an immune system weakness. Others were skeptical¹⁰, suggesting that it is only imagined. But the U.S. government's disease tracking agency, the Centers for Disease Control, offers assurance that chronic fatigue syndrome - CFS - is real.

One of the agency's leading scientists on the issue is Dr. William Reeves.

"One of the common stereotypes¹¹ is that this is a bunch of hysterical¹², upper class professional white women who are seeing physicians and have a mass hysteria," explained Dr. Reeves.  "People with CFS are as impaired, as a whole, as people with MS [multiple sclerosis], as people with AIDS, as people undergoing chemotherapy for cancer."

As evidence, Reeves points to a comprehensive government-funded study of 227 chronic fatigue syndrome patients in Wichita, Kansas, the results of which are published in 14 papers in the April issue of the journal Pharmacogenomics. The volunteers spent two days in a hospital ward¹³ undergoing detailed¹⁴ evaluations¹⁵ of their nervous systems, blood, sleep, cognitive¹⁶ function and the activity of 20,000 genes¹⁷.

The outcome shows that chronic fatigue syndrome has five different subtypes. But the common feature is that sufferers have certain genes that interfere¹⁸ with their ability to handle physical and environmental stress, such as illness, injury and various other adverse¹⁹ events.

"The results are groundbreaking," he added.  "Knowing that there is now a biological basis for CFS will help us identify ways to more effectively diagnose the illness and to come up with more effective treatments, including cognitive behavioral therapy, medications, or a combination of both."

The new research is the latest of several studies published within the past eight months implicating²⁰ certain genes in chronic fatigue syndrome. But the scientists say it will take time to identify the biological pathways involved.

In the United States, the government estimates that as many as one million people have the condition. It says the average family of a sufferer loses about $20,000 a year in earnings²¹ and savings²² due to missed work.

1 chronic   

adj.(疾病)长期未愈的，慢性的；极坏的

参考例句：

• Famine differs from chronic malnutrition.饥荒不同于慢性营养不良。
• Chronic poisoning may lead to death from inanition.慢性中毒也可能由虚弱导致死亡。

2 fatigue   

n.疲劳，劳累

参考例句：

• The old lady can't bear the fatigue of a long journey.这位老妇人不能忍受长途旅行的疲劳。
• I have got over my weakness and fatigue.我已从虚弱和疲劳中恢复过来了。

3 syndrome   

n.综合病症；并存特性

参考例句：

• The Institute says that an unidentified virus is to blame for the syndrome. 该研究所表示,引起这种综合症的是一种尚未确认的病毒。
• Results indicated that 11 fetuses had Down syndrome. 结果表明有11个胎儿患有唐氏综合征。

4 malady   

n.病，疾病(通常做比喻)

参考例句：

• There is no specific remedy for the malady.没有医治这种病的特效药。
• They are managing to control the malady into a small range.他们设法将疾病控制在小范围之内。

5 genetic   

adj.遗传的，遗传学的

参考例句：

• It's very difficult to treat genetic diseases.遗传性疾病治疗起来很困难。
• Each daughter cell can receive a full complement of the genetic information.每个子细胞可以收到遗传信息的一个完全补偿物。

6 makeup   

n.组织；性格；化装品

参考例句：

• Those who failed the exam take a makeup exam.这次考试不及格的人必须参加补考。
• Do you think her beauty could makeup for her stupidity?你认为她的美丽能弥补她的愚蠢吗？

7 elusive   

adj.难以表达(捉摸)的；令人困惑的；逃避的

参考例句：

• Try to catch the elusive charm of the original in translation.翻译时设法把握住原文中难以捉摸的风韵。
• Interpol have searched all the corners of the earth for the elusive hijackers.国际刑警组织已在世界各地搜查在逃的飞机劫持者。

8 joints   

接头( joint的名词复数 )； 关节； 公共场所（尤指价格低廉的饮食和娱乐场所） （非正式）； 一块烤肉 （英式英语）

参考例句：

• Expansion joints of various kinds are fitted on gas mains. 各种各样的伸缩接头被安装在煤气的总管道上了。
• Expansion joints of various kinds are fitted on steam pipes. 各种各样的伸缩接头被安装在蒸气管道上了。

9 impaired   

adj.受损的；出毛病的；有（身体或智力）缺陷的v.损害，削弱( impair的过去式和过去分词 )

参考例句：

• Much reading has impaired his vision. 大量读书损害了他的视力。 来自《现代汉英综合大词典》
• His hearing is somewhat impaired. 他的听觉已受到一定程度的损害。 来自《现代汉英综合大词典》

10 skeptical   

adj.怀疑的，多疑的

参考例句：

• Others here are more skeptical about the chances for justice being done.这里的其他人更为怀疑正义能否得到伸张。
• Her look was skeptical and resigned.她的表情是将信将疑而又无可奈何。

11 stereotypes   

n.老套，模式化的见解，有老一套固定想法的人( stereotype的名词复数 )v.把…模式化，使成陈规( stereotype的第三人称单数 )

参考例句：

• Such jokes tend to reinforce racial stereotypes. 这样的笑话容易渲染种族偏见。
• It makes me sick to read over such stereotypes devoid of content. 这种空洞无物的八股调，我看了就讨厌。 来自《现代汉英综合大词典》

12 hysterical   

adj.情绪异常激动的，歇斯底里般的

参考例句：

• He is hysterical at the sight of the photo.他一看到那张照片就异常激动。
• His hysterical laughter made everybody stunned.他那歇斯底里的笑声使所有的人不知所措。

13 ward   

n.守卫，监护，病房，行政区，由监护人或法院保护的人（尤指儿童）；vt.守护，躲开

参考例句：

• The hospital has a medical ward and a surgical ward.这家医院有内科病房和外科病房。
• During the evening picnic,I'll carry a torch to ward off the bugs.傍晚野餐时，我要点根火把，抵挡蚊虫。

14 detailed   

adj.详细的，详尽的，极注意细节的，完全的

参考例句：

• He had made a detailed study of the terrain.他对地形作了缜密的研究。
• A detailed list of our publications is available on request.我们的出版物有一份详细的目录备索。

15 evaluations   

估价( evaluation的名词复数 )； 赋值； 估计价值； [医学]诊断

参考例句：

• In fact, our moral evaluations are merely expressions of our desires. 事实上，我们的道德评价只是我们欲望的表达形式。 来自哲学部分
• Properly speaking, however, these evaluations and insights are not within the concept of official notice. 但准确地讲，这些评估和深远见识并未包括在官方通知概念里。

16 cognitive   

adj.认知的，认识的，有感知的

参考例句：

• As children grow older,their cognitive processes become sharper.孩子们越长越大，他们的认知过程变得更为敏锐。
• The cognitive psychologist is like the tinker who wants to know how a clock works.认知心理学者倒很像一个需要通晓钟表如何运转的钟表修理匠。

17 genes   

n.基因( gene的名词复数 )

参考例句：

• You have good genes from your parents, so you should live a long time. 你从父母那儿获得优良的基因，所以能够活得很长。 来自《简明英汉词典》
• Differences will help to reveal the functions of the genes. 它们间的差异将会帮助我们揭开基因多种功能。 来自英汉非文学 - 生命科学 - 生物技术的世纪

18 interfere   

v.(in)干涉，干预；(with)妨碍，打扰

参考例句：

• If we interfere, it may do more harm than good.如果我们干预的话，可能弊多利少。
• When others interfere in the affair,it always makes troubles. 别人一卷入这一事件，棘手的事情就来了。

19 adverse   

adj.不利的；有害的；敌对的，不友好的

参考例句：

• He is adverse to going abroad.他反对出国。
• The improper use of medicine could lead to severe adverse reactions.用药不当会产生严重的不良反应。

20 implicating   

vt.牵涉，涉及（implicate的现在分词形式）

参考例句：

• He was in the public dock, confessing everything, implicating everybody. 他站在被告席上，什么都招认，什么人都咬。 来自英汉文学
• No one would have had me get out of the scrape by implicating an old friend. 无论什么人都不能叫我为了自己摆脱困难便把一个老朋友牵累到这案子里去。 来自辞典例句

21 earnings   

n.工资收人；利润，利益，所得

参考例句：

• That old man lives on the earnings of his daughter.那个老人靠他女儿的收入维持生活。
• Last year there was a 20% decrease in his earnings.去年他的收入减少了20%。

22 savings   

n.存款，储蓄

参考例句：

• I can't afford the vacation,for it would eat up my savings.我度不起假，那样会把我的积蓄用光的。
• By this time he had used up all his savings.到这时，他的存款已全部用完。