VOA常速英语2007年-Stem Cell Research Dominates 2007 Medical Field

By Jessica Berman
Washington
19 December 2007

Stem cell research was the major medical and science story this past year, topping the list of achievements that experts say might finally lead to cures for many diseases. Meanwhile, global health officials also cheered progress in managing two killer¹ diseases. VOA's Jessica Berman has this look back at the health and medicine high points of 2007.

Stem cells are the master cells that have the ability to generate any cell in the human body. Scientists say this gives stem cells the potential to cure disease by being manipulated to become healthy or beneficial tissue.

In 2007, two teams of researchers, one in the United States and the other in Japan, announced they had succeeded in turning skin cells into a kind of stem cell, with an ability to transform into different cell types. The breakthrough bypassed the need to use embryonic³ stem cells.

James Thompson of the University of Wisconsin was one of the U.S. researchers who helped manipulate the skin cells. He says the development may help quell⁴ a fierce debate over the use of human embryos⁵ for research purposes

"I believe these new results, while they do not eliminate that controversy⁶, is probably the beginning of the end of that controversy," Thompson said.

American investigators⁷ provided the first evidence that the reprogrammed stem cells can work to cure disease, reversing a red-blood cell disorder⁸ known as sickle⁹ cell disease in mice.

Sickle cell is a genetic¹⁰ blood disease, mostly affecting children of African and Asian descent. In the devastating¹¹ disorder, red blood cells do not carry enough oxygen, causing severe pain and destruction of organs.

Investigators bred a strain of mice to contain the human sickle-cell gene². They then reprogrammed skin cells from the mice to an embryonic-like state, and coaxed¹² them to produce red blood cells.

When the mice received the new blood, they began producing normal blood and their symptoms went away.

In 2007, three men - Mario Capecchi of the University of Utah, Oliver Smithies of the University of North Carolina and Martin Evans of Cardiff University of Wales - won the Nobel Prize in Medicine for creating so-called knock-out mice, animals that make most genetic research possible.

"I would say our research is fundamentally resting upon these discoveries," Goldberg said.

Matthew Goldberg is neurologist at the University of Texas Southwestern in Dallas. He tries to find a cure for Parkinson's disease. His team uses knock-out mice to try to identify which genes¹³ are responsible for causing the debilitating¹⁴ condition.

In knock-out mice, Dr. Goldberg says certain genes have been silenced to mimic¹⁵ human disease.

"By deleting it [the gene], one can analyze¹⁶ what the behavior of the mouse is and what physiological¹⁷ changes occur, and thereby¹⁸ understand the normal function of that gene," he explained.

In 2007, there were also major developments in global public health.

The number of measles¹⁹ cases were slashed²⁰ in Africa by 91 percent, and 68 percent worldwide, thanks to an intensive vaccination²¹ campaign.

The Director of the U.S. Centers for Disease Control, Julie Gerberding, is part of a coalition²² of organizations called the Measles Initiative.

"We are celebrating this incredible progress. But we also have to acknowledge that 242,000 children dying of measles is still way too many," Gerberding said.

The Initiative said it is going to focus on efforts to vaccinate²³ children in South Asia, where most measles cases are now reported.

At the end of 2007, researchers report significant progress in the development of a malaria²⁴ vaccine²⁵. Ninety percent of the one-million children who get malaria worldwide each year live in sub-Saharan Africa.

In a trial in Mozambique, the experimental drug reduced the risk of two-thousand youngsters developing severe malaria by almost 60 percent.

Scientists say the vaccine, which is made by GlaxoSmithKline, could be available in two years.

1 killer   

n.杀人者，杀人犯，杀手，屠杀者

参考例句：

• Heart attacks have become Britain's No.1 killer disease.心脏病已成为英国的头号致命疾病。
• The bulk of the evidence points to him as her killer.大量证据证明是他杀死她的。

2 gene   

n.遗传因子，基因

参考例句：

• A single gene may have many effects.单一基因可能具有很多种效应。
• The targeting of gene therapy has been paid close attention.其中基因治疗的靶向性是值得密切关注的问题之一。

3 embryonic   

adj.胚胎的

参考例句：

• It is still in an embryonic stage.它还处于萌芽阶段。
• The plan,as yet,only exists in embryonic form.这个计划迄今为止还只是在酝酿之中。

4 quell   

v.压制，平息，减轻

参考例句：

• Soldiers were sent in to quell the riots.士兵们被派去平息骚乱。
• The armed force had to be called out to quell violence.不得不出动军队来镇压暴力行动。

5 embryos   

n.晶胚；胚，胚胎( embryo的名词复数 )

参考例句：

• Somatic cells of angiosperms enter a regenerative phase and behave like embryos. 被子植物体细胞进入一个生殖阶段，而且其行为象胚。 来自辞典例句
• Evolution can explain why human embryos look like gilled fishes. 进化论能够解释为什么人类的胚胎看起来象除去了内脏的鱼一样。 来自辞典例句

6 controversy   

n.争论，辩论，争吵

参考例句：

• That is a fact beyond controversy.那是一个无可争论的事实。
• We ran the risk of becoming the butt of every controversy.我们要冒使自己在所有的纷争中都成为众矢之的的风险。

7 investigators   

n.调查者，审查者( investigator的名词复数 )

参考例句：

• This memo could be the smoking gun that investigators have been looking for. 这份备忘录可能是调查人员一直在寻找的证据。
• The team consisted of six investigators and two secretaries. 这个团队由六个调查人员和两个秘书组成。 来自《简明英汉词典》

8 disorder   

n.紊乱，混乱；骚动，骚乱；疾病，失调

参考例句：

• When returning back,he discovered the room to be in disorder.回家后，他发现屋子里乱七八糟。
• It contained a vast number of letters in great disorder.里面七零八落地装着许多信件。

9 sickle   

n.镰刀

参考例句：

• The gardener was swishing off the tops of weeds with a sickle.园丁正在用镰刀嗖嗖地割掉杂草的顶端。
• There is a picture of the sickle on the flag. 旗帜上有镰刀的图案。

10 genetic   

adj.遗传的，遗传学的

参考例句：

• It's very difficult to treat genetic diseases.遗传性疾病治疗起来很困难。
• Each daughter cell can receive a full complement of the genetic information.每个子细胞可以收到遗传信息的一个完全补偿物。

11 devastating   

adj.毁灭性的，令人震惊的，强有力的

参考例句：

• It is the most devastating storm in 20 years.这是20年来破坏性最大的风暴。
• Affairs do have a devastating effect on marriages.婚外情确实会对婚姻造成毁灭性的影响。

12 coaxed   

v.哄，用好话劝说( coax的过去式和过去分词 )；巧言骗取；哄劝，劝诱

参考例句：

• She coaxed the horse into coming a little closer. 她哄着那匹马让它再靠近了一点。
• I coaxed my sister into taking me to the theatre. 我用好话哄姐姐带我去看戏。 来自《现代汉英综合大词典》

13 genes   

n.基因( gene的名词复数 )

参考例句：

• You have good genes from your parents, so you should live a long time. 你从父母那儿获得优良的基因，所以能够活得很长。 来自《简明英汉词典》
• Differences will help to reveal the functions of the genes. 它们间的差异将会帮助我们揭开基因多种功能。 来自英汉非文学 - 生命科学 - 生物技术的世纪

14 debilitating   

a.使衰弱的

参考例句：

• The debilitating disease made him too weak to work. 这个令他衰弱的病，使他弱到没有办法工作。
• You may soon leave one debilitating condition or relationship forever. 你即将永远地和这段霉运说拜拜了。

15 mimic   

v.模仿，戏弄；n.模仿他人言行的人

参考例句：

• A parrot can mimic a person's voice.鹦鹉能学人的声音。
• He used to mimic speech peculiarities of another.他过去总是模仿别人讲话的特点。

16 analyze   

vt.分析，解析 (=analyse)

参考例句：

• We should analyze the cause and effect of this event.我们应该分析这场事变的因果。
• The teacher tried to analyze the cause of our failure.老师设法分析我们失败的原因。

17 physiological   

adj.生理学的，生理学上的

参考例句：

• He bought a physiological book.他买了一本生理学方面的书。
• Every individual has a physiological requirement for each nutrient.每个人对每种营养成分都有一种生理上的需要。

18 thereby   

adv.因此，从而

参考例句：

• I have never been to that city,,ereby I don't know much about it.我从未去过那座城市，因此对它不怎么熟悉。
• He became a British citizen,thereby gaining the right to vote.他成了英国公民，因而得到了投票权。

19 measles   

n.麻疹，风疹，包虫病，痧子

参考例句：

• The doctor is quite definite about Tom having measles.医生十分肯定汤姆得了麻疹。
• The doctor told her to watch out for symptoms of measles.医生叫她注意麻疹出现的症状。

20 slashed   

v.挥砍( slash的过去式和过去分词 )；鞭打；割破；削减

参考例句：

• Someone had slashed the tyres on my car. 有人把我的汽车轮胎割破了。
• He slashed the bark off the tree with his knife. 他用刀把树皮从树上砍下。 来自《简明英汉词典》

21 vaccination   

n.接种疫苗，种痘

参考例句：

• Vaccination is a preventive against smallpox.种痘是预防天花的方法。
• Doctors suggest getting a tetanus vaccination every ten years.医生建议每十年注射一次破伤风疫苗。

22 coalition   

n.结合体，同盟，结合，联合

参考例句：

• The several parties formed a coalition.这几个政党组成了政治联盟。
• Coalition forces take great care to avoid civilian casualties.联盟军队竭尽全力避免造成平民伤亡。

23 vaccinate   

vt.给…接种疫苗；种牛痘

参考例句：

• Local health officials then can plan the best times to vaccinate people.这样，当地的卫生官员就可以安排最佳时间给人们接种疫苗。
• Doctors vaccinate us so that we do not catch smallpox.医生给我们打预防针使我们不会得天花。

24 malaria   

n.疟疾

参考例句：

• He had frequent attacks of malaria.他常患疟疾。
• Malaria is a kind of serious malady.疟疾是一种严重的疾病。

25 vaccine   

n.牛痘苗，疫苗；adj.牛痘的，疫苗的

参考例句：

• The polio vaccine has saved millions of lives.脊髓灰质炎疫苗挽救了数以百万计的生命。
• She takes a vaccine against influenza every fall.她每年秋季接种流感疫苗。