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(单词翻译:双击或拖选)
Vidushi Sinha | Washington, DC 18 May 2010
The World Health Organization calls antibiotic1 resistance one of the three greatest threats to human health.
Experts fear antibiotic resistance puts humans in danger of becoming nearly defenseless against some bacterial2 infections.
The World Health Organization calls antibiotic resistance one of the three greatest threats to human health.
Dangerous comeback
The improper3 use of antibiotics4 has led to strains of bacteria that are resistant5 to antibiotics. Experts say if efforts to combat the problem are not launched now, infections that were curable could make a dangerous comeback.
Dr. Thomas Frieden, director of the U.S. Centers for Disease Control and Prevention, calls on American lawmakers to address the problem.
"We speak of the pre-antibiotic and antibiotic eras, but if we don't improve our response to the public health problem of antibiotic resistance, we may enter a post- antibiotic world in which we will have few or no clinical interventions6 for some infections," he says.
Specialists are concerned that the more an antibiotic is used, the less effective it becomes. The genetic7 mutation8 of bacteria, which makes them resistant to antibiotics, is a natural process. But drug overuse has accelerated the process.
The improper use of antibiotics has led to strains of bacteria that are resistant to antibiotics.
Impact of drug overuse
"You end up with very resistant bacteria in the urinary tract9. That's only one example. Skin infections, lung infections, different bacteria causing these types of infections as they become more and more resistant, and then you get to more severe problem like tuberculosis10 in many parts of the world," says Dr. Donald Poretz, an infectious disease specialist. "People are given little of this and little of that to treat tuberculosis and tuberculosis germs develop resistance."
One of the most lethal11 infections born out of bacterial resistance is Methicillin-resistant Staphylococcus aureus, commonly known as MRSA which kills 19,000 people in the United States every year.
Since 2002, about 2 million MRSA infections have been acquired in US hospitals each year. Poretz says these infections can spread globally.
"You can have worldwide resistance, some resistant to some drugs, some resistant to other drugs in different parts of the world," he says. "And with rapid travel you can communicate those resistant bacteria to anyone here, there, there or there."
Cutting back
Drug companies have cut back on production of antibiotics, and that contributes to the problem, scientists say. Less than optimal12 dosing means the target bacteria survive and build resistance incrementally13.
Dr. Anthony Fauci of the National Institute of Allergy14 and Infectious Diseases (NIAID) says profits drive pharmaceutical15 companies to shy away from antibiotics.
"So if they're going to make a choice of making a product that some, a lot of, people are going to take every day for the rest of their lives, a lipid lowering agent, whatever you have, they're going to lean towards that rather than to make a new product that a relatively16 small proportion of the population will use maybe 10 days to two weeks out of the year," said Fauci.
Experts say the solution lies in educating patients and doctors to stop using antibiotics when they are not necessary.
1 antibiotic | |
adj.抗菌的;n.抗生素 | |
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2 bacterial | |
a.细菌的 | |
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3 improper | |
adj.不适当的,不合适的,不正确的,不合礼仪的 | |
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4 antibiotics | |
n.(用作复数)抗生素;(用作单数)抗生物质的研究;抗生素,抗菌素( antibiotic的名词复数 ) | |
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5 resistant | |
adj.(to)抵抗的,有抵抗力的 | |
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6 interventions | |
n.介入,干涉,干预( intervention的名词复数 ) | |
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7 genetic | |
adj.遗传的,遗传学的 | |
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8 mutation | |
n.变化,变异,转变 | |
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9 tract | |
n.传单,小册子,大片(土地或森林) | |
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10 tuberculosis | |
n.结核病,肺结核 | |
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11 lethal | |
adj.致死的;毁灭性的 | |
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12 optimal | |
adj.最适宜的;最理想的;最令人满意的 | |
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13 incrementally | |
adv.逐渐地 | |
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14 allergy | |
n.(因食物、药物等而引起的)过敏症 | |
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15 pharmaceutical | |
adj.药学的,药物的;药用的,药剂师的 | |
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16 relatively | |
adv.比较...地,相对地 | |
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