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(单词翻译:双击或拖选)
Helper Serum1 Boosts Effectiveness of Flu Vaccine2
Vaccines3 against swine and avian flu can be made more effective by the addition of a helper serum known as an adjuvant. The finding from a new study could let vaccine makers4 stretch supplies and possibly lower costs when new influenza5 strains emerge.
Influenza vaccines are generally effective against a particular strain of the flu. But microbiologist Hana Golding of the U.S Food and Drug Administration says sometimes a new strain emerges suddenly, and there is a scramble6 to design and manufacture a new vaccine.
"And you want to really, very quickly, vaccinate7 the population, you need all the help you can get," she says.
Vaccines are based on an antigen - the ingredient that actually stimulates8 the body's immune response - plus other components9.
A new study looked at the effectiveness of one of those other components - an adjuvant called MF59 - in boosting some flu vaccines.
"The MF59 is a class of adjuvant that is called oil-in-water emulsion, which is exactly what it says," Golding says. "This type of adjuvant works by attracting to the site of vaccination10 competent immune cells, whereby they're creating a local environment to facilitate the immune response."
In a study published in the journal Science Translational Medicine, Golding and her colleagues showed that adding MF59 to vaccines for H1N1 swine flu and for avian flu increased the immune response in various age groups.
One advantage of adding an adjuvant to a vaccine is that it may produce an equally effective dose using less antigen - the key ingredient that may be scarce or expensive in an emerging pandemic.
"If you have more efficient processing of a certain amount of vaccine, you don't need as much to get the same level of immune response. And if you can use less amount of vaccine per dose, then you can clearly have a much larger coverage11."
1 serum | |
n.浆液,血清,乳浆 | |
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2 vaccine | |
n.牛痘苗,疫苗;adj.牛痘的,疫苗的 | |
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3 vaccines | |
疫苗,痘苗( vaccine的名词复数 ) | |
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4 makers | |
n.制造者,制造商(maker的复数形式) | |
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5 influenza | |
n.流行性感冒,流感 | |
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6 scramble | |
v.爬行,攀爬,杂乱蔓延,碎片,片段,废料 | |
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7 vaccinate | |
vt.给…接种疫苗;种牛痘 | |
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8 stimulates | |
v.刺激( stimulate的第三人称单数 );激励;使兴奋;起兴奋作用,起刺激作用,起促进作用 | |
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9 components | |
(机器、设备等的)构成要素,零件,成分; 成分( component的名词复数 ); [物理化学]组分; [数学]分量; (混合物的)组成部分 | |
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10 vaccination | |
n.接种疫苗,种痘 | |
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11 coverage | |
n.报导,保险范围,保险额,范围,覆盖 | |
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