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(单词翻译:双击或拖选)
Scientists Gather for AIDS Vaccine1 2011
The largest conference on AIDS vaccine development is being held in Bangkok, Thailand FROM September 12th to the 15th. Researchers will discuss how to build on recent advances in a time of tight budgets.
Organizers of the conference, known as AV-2011, say a “safe and effective AIDS vaccine would be one of the greatest public health advances ever.” But they also admit it’s one of the “greatest scientific challenges.”
“This year’s meeting is particularly important in that the field’s at a very interesting place scientifically and institutionally in many respects. And this becomes a meeting where we will really get a sense of the enthusiasm that is clearly in the scientific community right now,” said
Mitchell Warren, head of AVAC, the AIDS Vaccine Advocacy Coalition2, who’s attending the Bangkok conference.
Getting back in the spotlight3
Much of the public attention on AIDS vaccine research has been diverted in recent months to what’s happening in prevention. Studies show that antiretroviral drugs – when taken by an infected person – can prevent HIV transmission to a non-infected person. They also show that non HIV infected people can take the drugs as a preventive measure known as pre-exposure prophylaxis.
But while there have been prevention advances, vaccine researchers are beginning new work to find what are called broadly neutralizing4 antibodies. If successful, these antibodies would be able to block the many, many different strains of HIV that now exist.
And Warren said there was the success in 2009 of the RV-144 trial in Thailand. It proved that an AIDS vaccine is possible. It was the largest AIDS vaccine trial ever, with thousands of participants.
“We got the result two years ago, but it’s not as if that trial ended. For the last two years, an international team of collaborators has been looking at the samples that were collected during the course of that trial to try to assess why that vaccine worked at all. When we got the result two years ago the community was excited, but kind of not sure why that vaccine worked. And many vaccines5 that we use in our public health systems, we actually don’t know why they work or how they work,” he said.
Working together
In the early days of AIDS vaccine research, collaboration6 was not as common as it is today. In fact, many believed the sharing of data could hurt a researcher’s chances of publishing the work and receiving credit for it.
Warren said, “One of the things that has most excited me as an advocate for AIDS vaccines over the last couple of years is not only the scientific progress, but I think even more than that (is) the level of collaboration and coordination7. For example, the collaborators coming out of RV-144 include over a hundred investigators8 in labs all over the world. People who might be seen as competitors in some ways are all collaborating9 to try to understand why we got the signal in RV-144 that we did.”
Warren is hopeful that collaboration and momentum10 can continue as budgets get tighter and tighter.
1 vaccine | |
n.牛痘苗,疫苗;adj.牛痘的,疫苗的 | |
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2 coalition | |
n.结合体,同盟,结合,联合 | |
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3 spotlight | |
n.公众注意的中心,聚光灯,探照灯,视听,注意,醒目 | |
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4 neutralizing | |
v.使失效( neutralize的现在分词 );抵消;中和;使(一个国家)中立化 | |
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5 vaccines | |
疫苗,痘苗( vaccine的名词复数 ) | |
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6 collaboration | |
n.合作,协作;勾结 | |
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7 coordination | |
n.协调,协作 | |
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8 investigators | |
n.调查者,审查者( investigator的名词复数 ) | |
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9 collaborating | |
合作( collaborate的现在分词 ); 勾结叛国 | |
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10 momentum | |
n.动力,冲力,势头;动量 | |
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