VOA标准英语2012--Drug-Resistant Malaria Threatens Effort to Control Disease

Drug-Resistant¹ Malaria² Threatens Effort to Control Disease

“The biggest fear is the resistance will spread across Southeast Asia and then spill over into Africa, where the vast majority of the 700,000 deaths a year [from malaria] occur. Historically, we have seen that when resistance to chloroquine [another anti-malaria drug] spread, there was an increase in mortality due to malaria. This is a very, very urgent situation,” said Tim Anderson, of the Texas Biomedical Research Institute, who spoke³ to us via Skype.

Anderson was part of the team that found evidence of growing resistance to artemesinin therapy for malaria in the border regions of Thailand and Burma, which they fear can spread westward⁴ across south east Asia and into Africa. The researchers are calling for immediate⁵ steps to control the spread of the resistant malaria parasite⁶.

The number of malaria deaths dropped in the last few years because of the artemisinin combination treatment, and Anderson predicts that mortality figures will rebound⁷ if the drug loses its efficacy.

“We are seeing that the drug kills the parasite 100-fold less well than it used to. That doesn’t mean that the parasites⁸ are not killed, so we can still cure patients. But the concern is that the number of patients who are NOT cured will rise. We currently estimate that about 30 percent of the patients are not cured with artemisinin,” said Anderson.

“I have to say that I am not actually all that surprised. Every time we have developed a new drug, the parasite has figured out a way to get around it,” said Dr. David Kaslow, the director of the PATH Malaria Vaccine⁹ Initiative - an international nonprofit organization committed to developing a malaria vaccine.

“The good news is that the first-ever malaria vaccine is on the horizon,” said Kaslow.

The malaria vaccine could be available by 2015, Kaslow said. But it will be just one more weapon against malaria, and the problem of resistance to artemisinin is real.

“It is a piece of a larger control and - hopefully, some day - elimination¹⁰ and eradication¹¹ program. We have to use a variety of tools - [including] bed nets, indoor residual¹² spraying, and preventive therapy,” said Kaslow.

Experts say drug-resistant strains of malaria likely will continue to emerge. The solution, they believe, is to support the development of new drugs and new therapies to fight the disease. 

1 resistant   

adj.(to)抵抗的，有抵抗力的

参考例句：

• Many pests are resistant to the insecticide.许多害虫对这种杀虫剂有抵抗力。
• They imposed their government by force on the resistant population.他们以武力把自己的统治强加在持反抗态度的人民头上。

2 malaria   

n.疟疾

参考例句：

• He had frequent attacks of malaria.他常患疟疾。
• Malaria is a kind of serious malady.疟疾是一种严重的疾病。

3 spoke   

n.（车轮的）辐条；轮辐；破坏某人的计划；阻挠某人的行动 v.讲，谈（speak的过去式）；说；演说；从某种观点来说

参考例句：

• They sourced the spoke nuts from our company.他们的轮辐螺帽是从我们公司获得的。
• The spokes of a wheel are the bars that connect the outer ring to the centre.辐条是轮子上连接外圈与中心的条棒。

4 westward   

n.西方，西部；adj.西方的，向西的；adv.向西

参考例句：

• We live on the westward slope of the hill.我们住在这座山的西山坡。
• Explore westward or wherever.向西或到什么别的地方去勘探。

5 immediate   

adj.立即的；直接的，最接近的；紧靠的

参考例句：

• His immediate neighbours felt it their duty to call.他的近邻认为他们有责任去拜访。
• We declared ourselves for the immediate convocation of the meeting.我们主张立即召开这个会议。

6 parasite   

n.寄生虫；寄生菌；食客

参考例句：

• The lazy man was a parasite on his family.那懒汉是家里的寄生虫。
• I don't want to be a parasite.I must earn my own way in life.我不想做寄生虫，我要自己养活自己。

7 rebound   

v.弹回；n.弹回，跳回

参考例句：

• The vibrations accompanying the rebound are the earth quake.伴随这种回弹的振动就是地震。
• Our evil example will rebound upon ourselves.我们的坏榜样会回到我们自己头上的。

8 parasites   

寄生物( parasite的名词复数 )； 靠他人为生的人； 诸虫

参考例句：

• These symptoms may be referable to virus infection rather than parasites. 这些症状也许是由病毒感染引起的，而与寄生虫无关。
• Kangaroos harbor a vast range of parasites. 袋鼠身上有各种各样的寄生虫。

9 vaccine   

n.牛痘苗，疫苗；adj.牛痘的，疫苗的

参考例句：

• The polio vaccine has saved millions of lives.脊髓灰质炎疫苗挽救了数以百万计的生命。
• She takes a vaccine against influenza every fall.她每年秋季接种流感疫苗。

10 elimination   

n.排除，消除，消灭

参考例句：

• Their elimination from the competition was a great surprise.他们在比赛中遭到淘汰是个很大的意外。
• I was eliminated from the 400 metres in the semi-finals.我在400米半决赛中被淘汰。

11 eradication   

n.根除

参考例句：

• The eradication of an established infestation is not easy. 根除昆虫蔓延是不容易的。
• This is often required for intelligent control and eradication. 这经常需要灵巧的控制与消除。

12 residual   

adj.复播复映追加时间；存留下来的，剩余的

参考例句：

• There are still a few residual problems with the computer program.电脑程序还有一些残留问题。
• The resulting residual chromatism is known as secondary spectrum.所得到的剩余色差叫做二次光谱。