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This is Scientific American's 60-Second Science. I'm Christopher Intagliata. Got a minute?
Doctors prescribe Ritalin to hyperactive kids to calm them down and increase their attention span. And college kids have taken to using Ritalin to concentrate when they hit the books. But it hasn't been clear how the drug boosts focus. Now a paper in the journal Biological Psychiatry1 suggests how it might work. Neuronscientists dosed rats with Ritalin and had them perform the kind of working memory task ADHD patients have trouble with. At the same time,they measured neural2 activity with tiny-electrodes implanted in the rats' brains.At low doses Ritalin primarily affected3 the prefrontal cortex,jacking up its sensitivity to signals coming in from the hippocampus.And here is how the drugs seemed to help with attention,it strengthened choruses of neurons firing together and put a damper on scattered4 uncoordinated activity. But at high doses the profrontal cortex tuned5 out and Ritalin's effects were similar to those of other stimulants6.The rats lost their cognitive7 edge and they became hyperactive,sniffing and licking repetitively.So Ritalin shows you can indeed have too much of a good thing to the point of distraction8.
Thanks for the minute for Scientific American's 60-Second Science. I am Christopher Intagliata.
WORDS AND EXPRESSIONS:
Hippocampus: The hippocampus is a part of the forebrain, located in the medial temporal lobe9.
1 psychiatry | |
n.精神病学,精神病疗法 | |
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2 neural | |
adj.神经的,神经系统的 | |
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3 affected | |
adj.不自然的,假装的 | |
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4 scattered | |
adj.分散的,稀疏的;散步的;疏疏落落的 | |
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5 tuned | |
adj.调谐的,已调谐的v.调音( tune的过去式和过去分词 );调整;(给收音机、电视等)调谐;使协调 | |
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6 stimulants | |
n.兴奋剂( stimulant的名词复数 );含兴奋剂的饮料;刺激物;激励物 | |
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7 cognitive | |
adj.认知的,认识的,有感知的 | |
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8 distraction | |
n.精神涣散,精神不集中,消遣,娱乐 | |
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9 lobe | |
n.耳垂,(肺,肝等的)叶 | |
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