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Scientists Trained Rats to Drive Cars. What Did They Learn?
Mice and rats have long been used in medical research because of their biological similarities to humans.
The tiny animals have already shown an ability to recognize objects, push buttons and find their way through complex paths.
Now, scientists have trained rats to drive small vehicles created for them. One of the main findings1 of the experiment was that the driving activity seemed to help the rats relax.
Researchers at the University of Richmond in Virginia led the experiment. Their findings were published in Behavioural Brain Research.
The team built tiny cars out of plastic and other materials. The vehicles had an opening at one end where electrical wires were attached. By touching2 one of three different wires, the rat could steer3 the car in different directions – left, center and right.
Sweet treats were placed inside the experiment containers in an attempt to get the rats to drive the vehicle to get to the food.
Researchers trained 17 rats over several months to drive around the containers. The animals proved that they could be trained to drive forward as well as in other directions to get to the treats.
Kelly Lambert of the University of Richmond helped lead the experiment. She told the French news agency4 AFP the research suggests that rat brains may be more complex and flexible than once thought.
Lambert said she had long been interested in neuroplasticity, or the way the brain changes to react to different experiences and difficulties. She found that rats kept in what she calls "enriched6 environments" performed far better than those in labs. While she expected that result, Lambert told AFP "it was actually quite shocking7 to me that they were so much better."
The researchers examined levels of two hormones9 in the rats – one that causes stress and another that counters it. All rats that took part in the training had higher levels of the hormone8 that reduces stress. The research suggests the increased relaxation10 levels could be linked to the enjoyment11 of successfully completing a new skill.
The team also found that the rats that drove themselves showed higher levels of the stress-fighting hormone than those that simply rode in small cars controlled by humans.
Lambert said the most exciting result of the experiment for her was about the possible effect on humans. The research may open new areas of non-drug treatments for people suffering from mental health conditions.
"There's no cure for schizophrenia or depression and we need to catch up," she said. "And I think we need to look at different animal models and different types of tasks and really respect that behavior can change our neurochemistry."
Speaking to the British-based magazine New Scientist, Lambert said her team is planning to continue experiments to learn more about how the rats learned12 to drive. The new research will also examine why some activities appear to reduce stress, and which areas of the brain are involved in the process.
As an example, Lambert said new driving tests could be created to test the effects of Parkinson's disease13 on motor skills and awareness14 of space. "If we use more realistic and challenging models, it may provide more meaningful data," she told New Scientist.
Words in This Story
button – n. something you press to control a piece of equipment
relax – v. to become happy and comfortable because nothing is worrying you
steer – v. to control the direction of a vehicle
treat – n. a piece of free food, drink, etc., provided15 to someone
flexible – adj. able to be easily changed
enrich5 – v. to improve the quality of something by adding something to it
hormone – n. one of several chemicals produced in the body that influence growth and development
stress – n. feelings or worry or nervousness caused by difficult situations or problems
task – n. a piece of work, especially something unpleasant or difficult
1 findings | |
n.发现物( finding的名词复数 );调查(或研究)的结果;(陪审团的)裁决 | |
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2 touching | |
adj.动人的,使人感伤的 | |
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3 steer | |
vt.驾驶,为…操舵;引导;vi.驾驶 | |
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4 agency | |
n.经办;代理;代理处 | |
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5 enrich | |
vt.充实,使丰富,使富裕,使富有 | |
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6 enriched | |
使富有( enrich的过去式和过去分词 ); 使富裕; 充实; 使丰富 | |
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7 shocking | |
adj.令人气愤的;令人震惊的 | |
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8 hormone | |
n.荷尔蒙,激素,内分泌 | |
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9 hormones | |
n. 荷尔蒙,激素 名词hormone的复数形式 | |
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10 relaxation | |
n.松弛,放松;休息;消遣;娱乐 | |
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11 enjoyment | |
n.乐趣;享有;享用 | |
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12 learned | |
adj.有学问的,博学的;learn的过去式和过去分词 | |
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13 disease | |
n.疾病,弊端 | |
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14 awareness | |
n.意识,觉悟,懂事,明智 | |
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15 provided | |
conj.假如,若是;adj.预备好的,由...供给的 | |
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